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Exquisite allele discrimination by toehold hairpin primers
The ability to detect and monitor single nucleotide polymorphisms (SNPs) in biological samples is an enabling research and clinical tool. We have developed a surprising, inexpensive primer design method that provides exquisite discrimination between SNPs. The field of DNA computation is largely reli...
Autores principales: | Byrom, Michelle, Bhadra, Sanchita, Jiang, Yu Sherry, Ellington, Andrew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150758/ https://www.ncbi.nlm.nih.gov/pubmed/24990378 http://dx.doi.org/10.1093/nar/gku558 |
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