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HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway

Kaposi's sarcoma (KS) is an AIDS-defining cancer with aberrant neovascularization caused by KS-associated herpesvirus (KSHV). Although the interaction between HIV-1 and KSHV plays a pivotal role in promoting the aggressive manifestations of KS, the pathogenesis underlying AIDS-KS remains largel...

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Detalles Bibliográficos
Autores principales: Xue, Min, Yao, Shuihong, Hu, Minmin, Li, Wan, Hao, Tingting, Zhou, Feng, Zhu, Xiaofei, Lu, Hongmei, Qin, Di, Yan, Qin, Zhu, Jianzhong, Gao, Shou-Jiang, Lu, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150761/
https://www.ncbi.nlm.nih.gov/pubmed/25104021
http://dx.doi.org/10.1093/nar/gku583