Repair of O(6)-methylguanine adducts in human telomeric G-quadruplex DNA by O(6)-alkylguanine-DNA alkyltransferase

O(6)-alkylguanine-DNA alkyltransferase (AGT) is a single-cycle DNA repair enzyme that removes pro-mutagenic O(6)-alkylguanine adducts from DNA. Its functions with short single-stranded and duplex substrates have been characterized, but its ability to act on other DNA structures remains poorly unders...

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Detalles Bibliográficos
Autores principales: Hellman, Lance M., Spear, Tyler J., Koontz, Colton J., Melikishvili, Manana, Fried, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150771/
https://www.ncbi.nlm.nih.gov/pubmed/25080506
http://dx.doi.org/10.1093/nar/gku659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150771/
https://www.ncbi.nlm.nih.gov/pubmed/25080506
http://dx.doi.org/10.1093/nar/gku659

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