A-to-I editing in the miRNA seed region regulates target mRNA selection and silencing efficiency

Hydrolytic deamination of adenosine to inosine (A-to-I) by adenosine deaminases acting on RNA (ADARs) is a post-transcriptional modification which results in a discrepancy between genomic DNA and the transcribed RNA sequence, thus contributing to the diversity of the transcriptome. Inosine preferent...

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Detalles Bibliográficos
Autores principales: Kume, Hideaki, Hino, Kimihiro, Galipon, Josephine, Ui-Tei, Kumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150774/
https://www.ncbi.nlm.nih.gov/pubmed/25056317
http://dx.doi.org/10.1093/nar/gku662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150774/
https://www.ncbi.nlm.nih.gov/pubmed/25056317
http://dx.doi.org/10.1093/nar/gku662

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