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Functional gene groups are concentrated within chromosomes, among chromosomes and in the nuclear space of the human genome
Genomes undergo changes in organization as a result of gene duplications, chromosomal rearrangements and local mutations, among other mechanisms. In contrast to prokaryotes, in which genes of a common function are often organized in operons and reside contiguously along the genome, most eukaryotes s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150778/ https://www.ncbi.nlm.nih.gov/pubmed/25056310 http://dx.doi.org/10.1093/nar/gku667 |