Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair

Individuals with Fanconi anemia (FA) are susceptible to bone marrow failure, congenital abnormalities, cancer predisposition and exhibit defective DNA crosslink repair. The relationship of this repair defect to disease traits remains unclear, given that crosslink sensitivity is recapitulated in FA m...

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Detalles Bibliográficos
Autores principales: Larin, Meghan, Gallo, David, Tamblyn, Laura, Yang, Jay, Liao, Hudson, Sabat, Nestor, Brown, Grant W., McPherson, J. Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150781/
https://www.ncbi.nlm.nih.gov/pubmed/25056314
http://dx.doi.org/10.1093/nar/gku676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150781/
https://www.ncbi.nlm.nih.gov/pubmed/25056314
http://dx.doi.org/10.1093/nar/gku676

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