Chimeric bifunctional oligonucleotides as a novel tool to invade telomerase assembly

Telomerase is a key participant in the telomere length maintaining system in eukaryotic cells. Telomerase RNA and protein reverse transcriptase subunits are essential for the appearance of active telomerase in vitro. Telomerase is active in many cancer types and is a potential target for anticancer...

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Detalles Bibliográficos
Autores principales: Azhibek, Dulat, Zvereva, Maria, Zatsepin, Timofei, Rubtsova, Maria, Dontsova, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150790/
https://www.ncbi.nlm.nih.gov/pubmed/25081209
http://dx.doi.org/10.1093/nar/gku688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150790/
https://www.ncbi.nlm.nih.gov/pubmed/25081209
http://dx.doi.org/10.1093/nar/gku688

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