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Major alteration in coxsackievirus B3 genomic RNA structure distinguishes a virulent strain from an avirulent strain

Coxsackievirus B3 (CV-B3) is a cardiovirulent enterovirus that utilizes a 5′ untranslated region (5′UTR) to complete critical viral processes. Here, we directly compared the structure of a 5′UTR from a virulent strain with that of a naturally occurring avirulent strain. Using chemical probing analys...

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Detalles Bibliográficos
Autores principales: Prusa, Jerome, Missak, Johanna, Kittrell, Jeff, Evans, John J., Tapprich, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150801/
https://www.ncbi.nlm.nih.gov/pubmed/25074382
http://dx.doi.org/10.1093/nar/gku706