ATP insertion opposite 8-oxo-deoxyguanosine by Pol4 mediates error-free tolerance in Schizosaccharomyces pombe

7,8-Dihydro-8-oxo-deoxyguanosine (8oxodG) is a highly premutagenic DNA lesion due to its ability to mispair with adenine. Schizosaccharomyces pombe lacks homologs for relevant enzymes that repair 8oxodG, which suggests that this lesion could be persistent and must be tolerated. Here we show that SpP...

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Detalles Bibliográficos
Autores principales: Sastre-Moreno, Guillermo, Sánchez, Arancha, Esteban, Verónica, Blanco, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150805/
https://www.ncbi.nlm.nih.gov/pubmed/25106870
http://dx.doi.org/10.1093/nar/gku711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150805/
https://www.ncbi.nlm.nih.gov/pubmed/25106870
http://dx.doi.org/10.1093/nar/gku711

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