HCMV pUL135 Remodels the Actin Cytoskeleton to Impair Immune Recognition of Infected Cells

Immune evasion genes help human cytomegalovirus (HCMV) establish lifelong persistence. Without immune pressure, laboratory-adapted HCMV strains have undergone genetic alterations. Among these, the deletion of the U(L)/b’ domain is associated with loss of virulence. In a screen of U(L)/b’, we identif...

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Detalles Bibliográficos
Autores principales: Stanton, Richard J., Prod’homme, Virginie, Purbhoo, Marco A., Moore, Melanie, Aicheler, Rebecca J., Heinzmann, Marcus, Bailer, Susanne M., Haas, Jürgen, Antrobus, Robin, Weekes, Michael P., Lehner, Paul J., Vojtesek, Borivoj, Miners, Kelly L., Man, Stephen, Wilkie, Gavin S., Davison, Andrew J., Wang, Eddie C.Y., Tomasec, Peter, Wilkinson, Gavin W.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150922/
https://www.ncbi.nlm.nih.gov/pubmed/25121749
http://dx.doi.org/10.1016/j.chom.2014.07.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150922/
https://www.ncbi.nlm.nih.gov/pubmed/25121749
http://dx.doi.org/10.1016/j.chom.2014.07.005

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