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Translation of Anticancer Efficacy From Nonclinical Models to the Clinic

Mouse cancer models have provided critical insights into tumor biology; however, clinical translation of these findings has been challenging. This perspective posits that factors impacting on successful translation start with limitations in capturing human cancer pathophysiology and end with challen...

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Detalles Bibliográficos
Autores principales: Stroh, M, Duda, D G, Takimoto, C H, Yamazaki, S, Vicini, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150926/
https://www.ncbi.nlm.nih.gov/pubmed/25098530
http://dx.doi.org/10.1038/psp.2014.28