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Predicting QTc Prolongation in Man From Only In Vitro Data

Mishra et al.(1) in their article “Interaction between domperidone and ketoconazole: toward prediction of consequent QTc prolongation using purely in vitro information” describe the use of physiologically based pharmacokinetic (PBPK) modeling and pharmacodynamic models of cardiac repolarization to p...

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Detalles Bibliográficos
Autor principal: Leishman, D J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150928/
https://www.ncbi.nlm.nih.gov/pubmed/25141222
http://dx.doi.org/10.1038/psp.2014.33