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Cytoadherence phenotype of Plasmodium falciparum-infected erythrocytes is associated with specific pfemp-1 expression in parasites from children with cerebral malaria

BACKGROUND: Cytoadherence of Plasmodium falciparum-infected erythrocytes (IEs) in deep microvasculature endothelia plays a major role in the pathogenesis of cerebral malaria (CM). This biological process is thought to be mediated by P. falciparum erythrocyte membrane protein-1 (PfEMP-1) and human re...

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Detalles Bibliográficos
Autores principales: Almelli, Talleh, Ndam, Nicaise T, Ezimegnon, Sem, Alao, Maroufou J, Ahouansou, Charles, Sagbo, Gratien, Amoussou, Annick, Deloron, Philippe, Tahar, Rachida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150962/
https://www.ncbi.nlm.nih.gov/pubmed/25156105
http://dx.doi.org/10.1186/1475-2875-13-333