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Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3σ

Wig-1, also known as ZMAT3, is a p53 target gene that encodes an RNA-binding zinc-finger protein involved in the regulation of mRNA stability through binding to AU-rich elements (AREs). We have used microarray analysis to identify novel Wig-1 target mRNAs. We identified 2447 transcripts with >fou...

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Detalles Bibliográficos
Autores principales: Bersani, C, Xu, L-D, Vilborg, A, Lui, W-O, Wiman, K G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150987/
https://www.ncbi.nlm.nih.gov/pubmed/24469038
http://dx.doi.org/10.1038/onc.2013.594