Geneva Cocktail for Cytochrome P450 and P-Glycoprotein Activity Assessment Using Dried Blood Spots

The suitability of the capillary dried blood spot (DBS) sampling method was assessed for simultaneous phenotyping of cytochrome P450 (CYP) enzymes and P-glycoprotein (P-gp) using a cocktail approach. Ten volunteers received an oral cocktail capsule containing low doses of the probes bupropion (CYP2B...

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Detalles Bibliográficos
Autores principales: Bosilkovska, M, Samer, C F, Déglon, J, Rebsamen, M, Staub, C, Dayer, P, Walder, B, Desmeules, J A, Daali, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151019/
https://www.ncbi.nlm.nih.gov/pubmed/24722393
http://dx.doi.org/10.1038/clpt.2014.83

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151019/
https://www.ncbi.nlm.nih.gov/pubmed/24722393
http://dx.doi.org/10.1038/clpt.2014.83

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