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Geneva Cocktail for Cytochrome P450 and P-Glycoprotein Activity Assessment Using Dried Blood Spots
The suitability of the capillary dried blood spot (DBS) sampling method was assessed for simultaneous phenotyping of cytochrome P450 (CYP) enzymes and P-glycoprotein (P-gp) using a cocktail approach. Ten volunteers received an oral cocktail capsule containing low doses of the probes bupropion (CYP2B...
Autores principales: | Bosilkovska, M, Samer, C F, Déglon, J, Rebsamen, M, Staub, C, Dayer, P, Walder, B, Desmeules, J A, Daali, Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151019/ https://www.ncbi.nlm.nih.gov/pubmed/24722393 http://dx.doi.org/10.1038/clpt.2014.83 |
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