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Visualization of the physical and functional interaction between hMYH and hRad9 by Dronpa bimolecular fluorescence complementation

BACKGROUND: Human MutY glycosylase homolog (hMYH), a component of the base excision repair pathway, is responsible for the generation of apurinic/apyrimidinic sites. Rad9-Rad1-Hus1 (9-1-1) is a heterotrimeric protein complex that plays a role in cell cycle checkpoint control and DNA repair. In human...

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Detalles Bibliográficos
Autores principales: Agustina, Lia, Hahm, Soo-Hyun, Han, Se Hee, Tran, An Hue Vy, Chung, Ji Hyung, Park, Jong-Hwa, Park, Jin Woo, Han, Ye Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151078/
https://www.ncbi.nlm.nih.gov/pubmed/25127721
http://dx.doi.org/10.1186/1471-2199-15-17