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Processed pseudogene insertions in somatic cells

Processed pseudogenes are copies of messenger RNAs that have been reverse transcribed into DNA and inserted into the genome using the enzymatic activities of active L1 elements. Processed pseudogenes generally lack introns, end in a 3’ poly A, and are flanked by target site duplications. Until recen...

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Detalles Bibliográficos
Autor principal: Kazazian, Haig H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151081/
https://www.ncbi.nlm.nih.gov/pubmed/25184004
http://dx.doi.org/10.1186/1759-8753-5-20