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Sequential and ordered assembly of a large DNA repair complex on undamaged chromatin

In nucleotide excision repair (NER), damage recognition by XPC-hHR23b is described as a critical step in the formation of the preincision complex (PInC) further composed of TFIIH, XPA, RPA, XPG, and ERCC1-XPF. To obtain new molecular insights into the assembly of the PInC, we analyzed its formation...

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Detalles Bibliográficos
Autores principales: Ziani, Salim, Nagy, Zita, Alekseev, Sergey, Soutoglou, Evi, Egly, Jean-Marc, Coin, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151144/
https://www.ncbi.nlm.nih.gov/pubmed/25154395
http://dx.doi.org/10.1083/jcb.201403096