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Adjuvant-dependent regulation of interleukin-17 expressing γδ T cells and inhibition of Th2 responses in allergic airways disease

BACKGROUND: Th2 immune responses are linked primarily to mild and moderate asthma, while Th17 cells, Interleukin-17A (IL-17) and neutrophilia have been implicated in more severe forms of disease. How Th2-dependent allergic reactions are influenced by Th17 and IL-17-γδ T cells is poorly understood. I...

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Detalles Bibliográficos
Autores principales: Nakada, Emily M, Shan, Jichuan, Kinyanjui, Margaret W, Fixman, Elizabeth D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151193/
https://www.ncbi.nlm.nih.gov/pubmed/25123451
http://dx.doi.org/10.1186/s12931-014-0090-5