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Detection of disease-associated α-synuclein in the cerebrospinal fluid: a feasibility study

With the aim to evaluate the significance and reliability of detecting disease-specific α-synuclein in the cerebrospinal fluid (CSF) we developed an ELISA and bead-assay. We used a commercial antibody (5G4) that does not bind to the physiological monomeric form of α-synuclein, but is highly specific...

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Detalles Bibliográficos
Autores principales: Unterberger, Ursula, Lachmann, Ingolf, Voigtländer, Till, Pirker, Walter, Berghoff, Anna S., Flach, Katharina, Wagner, Uta, Geneste, Aline, Perret-Liaudet, Armand, Kovacs, Gabor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dustri-Verlag Dr. Karl Feistle 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151342/
https://www.ncbi.nlm.nih.gov/pubmed/25131945
http://dx.doi.org/10.5414/NP300796