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Inhibition of leptin-induced vascular extracellular matrix remodelling by adiponectin

Vascular extracellular matrix (ECM) remodelling, which is the result of disruption in the balance of ECM synthesis and degradation, induces vessel fibrosis and thereby leads to hypertension. Leptin is known to promote tissue fibrosis, while adiponectin has recently been demonstrated to be anti-fibro...

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Detalles Bibliográficos
Autores principales: Zhang, Zhi, Wang, Fang, Wang, Bing-jian, Chu, Guang, Cao, Qunan, Sun, Bao-Gui, Dai, Qiu-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151455/
https://www.ncbi.nlm.nih.gov/pubmed/24982243
http://dx.doi.org/10.1530/JME-14-0027