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The histamine H(4) receptor mediates inflammation and Th17 responses in preclinical models of arthritis

OBJECTIVE: The histamine H(4) receptor (H(4)R) has been shown to drive inflammatory responses in models of asthma, colitis and dermatitis, and in these models it appears to affect both innate and adaptive immune responses. In this study, we used both H(4)R-deficient mice and a specific H(4)R antagon...

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Detalles Bibliográficos
Autores principales: Cowden, Jeffery M, Yu, Fuqu, Banie, Homayon, Farahani, Mandana, Ling, Ping, Nguyen, Steven, Riley, Jason P, Zhang, Mai, Zhu, Jian, Dunford, Paul J, Thurmond, Robin L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151522/
https://www.ncbi.nlm.nih.gov/pubmed/24126456
http://dx.doi.org/10.1136/annrheumdis-2013-203832