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Exendin-4, a glucagon-like peptide-1 receptor agonist, inhibits hyperglycemia-induced apoptosis in myocytes by suppressing receptor for advanced glycation end products expression

Activation of the receptor for advanced glycation end products (RAGE) axis may have an important role in apoptosis. Glucagon-like peptide-1 (GLP-1) is a gut hormone that has been proposed as a therapeutic target for the treatment of diabetes, and GLP-1 receptor agonists have been reported to protect...

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Detalles Bibliográficos
Autores principales: YI, BO, HU, XIAORONG, WEN, ZHONGYUAN, ZHANG, TING, CAI, YULI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151638/
https://www.ncbi.nlm.nih.gov/pubmed/25187821
http://dx.doi.org/10.3892/etm.2014.1873