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Phosphorylation at Y1065 in Vinculin Mediates Actin Bundling, Cell Spreading, and Mechanical Responses to Force

[Image: see text] Vinculin is an essential structural adaptor protein that localizes to sites of adhesion and is involved in a number of cell processes including adhesion, spreading, motility, force transduction, and cell survival. The C-terminal vinculin tail domain (Vt) contains the necessary stru...

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Detalles Bibliográficos
Autores principales: Tolbert, Caitlin E., Thompson, Peter M., Superfine, Richard, Burridge, Keith, Campbell, Sharon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151700/
https://www.ncbi.nlm.nih.gov/pubmed/25115937
http://dx.doi.org/10.1021/bi500678x