Hydroxyproline-Derived Pseudoenantiomeric [2.2.1] Bicyclic Phosphines: Asymmetric Synthesis of (+)- and (−)-Pyrrolines

[Image: see text] We have prepared two new diastereoisomeric 2-aza-5-phosphabicyclo[2.2.1]heptanes from naturally occurring trans-4-hydroxy-l-proline in six chemical operations. These syntheses are concise and highly efficient, with straightforward purification. When we used these chiral phosphines...

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Detalles Bibliográficos
Autores principales: Henry, Christopher E., Xu, Qihai, Fan, Yi Chiao, Martin, Tioga J., Belding, Lee, Dudding, Travis, Kwon, Ohyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151783/
https://www.ncbi.nlm.nih.gov/pubmed/25099350
http://dx.doi.org/10.1021/ja505592h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151783/
https://www.ncbi.nlm.nih.gov/pubmed/25099350
http://dx.doi.org/10.1021/ja505592h

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