Preclinical antitumor activity of SST0116CL1: A novel heat shock protein 90 inhibitor

4-Amino substituted resorcino-isoxazole (SST0116CL1) (property of Sigma-Tau Research Switzerland S.A.) is a potent, second generation, small-molecule heat shock protein 90 inhibitor (Hsp90i). SST0116CL1 binds to the ATP binding pocket of Hsp90, and interferes with Hsp90 chaperone function thus resul...

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Detalles Bibliográficos
Autores principales: VESCI, LOREDANA, MILAZZO, FERDINANDO MARIA, CAROLO, VALERIA, PACE, SILVIA, GIANINI, GIUSEPE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151799/
https://www.ncbi.nlm.nih.gov/pubmed/25096516
http://dx.doi.org/10.3892/ijo.2014.2575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151799/
https://www.ncbi.nlm.nih.gov/pubmed/25096516
http://dx.doi.org/10.3892/ijo.2014.2575

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