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Auranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53

Auranofin is a gold-containing compound classified by the World Health Organization as a clinically established rheumatoid arthritis therapeutic agent. Through drug screening for novel anticancer therapeutics, we unexpectedly identified auranofin as a potent anticancer agent against a p53-null ovari...

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Detalles Bibliográficos
Autores principales: PARK, SEE-HYOUN G, LEE, JUN GHAN, BEREK, JONATHAN S., HU, MICKE Y C.-T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151813/
https://www.ncbi.nlm.nih.gov/pubmed/25096914
http://dx.doi.org/10.3892/ijo.2014.2579