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Sulforaphane, quercetin and catechins complement each other in elimination of advanced pancreatic cancer by miR-let-7 induction and K-ras inhibition

Pancreatic ductal adenocarcinoma (PDA) has the worst prognosis of all malignancies, and current therapeutic options do not target cancer stem cells (CSCs), which may be the reason for the extreme aggressiveness. The dietary agents sulforaphane and quercetin enriched e.g., in broccoli, and the main a...

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Detalles Bibliográficos
Autores principales: APPARI, MAHESH, BABU, KAMESH R., KACZOROWSKI, ADAM, GROSS, WOLFGANG, HERR, INGRID
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151818/
https://www.ncbi.nlm.nih.gov/pubmed/25017900
http://dx.doi.org/10.3892/ijo.2014.2539