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Therapeutic Targeting of Integrin αvβ6 in Breast Cancer

BACKGROUND: Integrin αvβ6 promotes migration, invasion, and survival of cancer cells; however, the relevance and role of αvβ6 has yet to be elucidated in breast cancer. METHODS: Protein expression of integrin subunit beta6 (β6) was measured in breast cancers by immunohistochemistry (n > 2000) and...

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Detalles Bibliográficos
Autores principales: Moore, Kate M., Thomas, Gareth J., Duffy, Stephen W., Warwick, Jane, Gabe, Rhian, Chou, Patrick, Ellis, Ian O., Green, Andrew R., Haider, Syed, Brouilette, Kellie, Saha, Antonio, Vallath, Sabari, Bowen, Rebecca, Chelala, Claude, Eccles, Diana, Tapper, William J., Thompson, Alastair M., Quinlan, Phillip, Jordan, Lee, Gillett, Cheryl, Brentnall, Adam, Violette, Shelia, Weinreb, Paul H., Kendrew, Jane, Barry, Simon T., Hart, Ian R., Jones, J. Louise, Marshall, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151855/
https://www.ncbi.nlm.nih.gov/pubmed/24974129
http://dx.doi.org/10.1093/jnci/dju169