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Glucose Kinetics in the Collagen-Induced Arthritis Model: An All-in-One Model to Assess Both Efficacy and Metabolic Side Effects of Glucocorticoids

Prednisolone and other glucocorticoids (GCs) are potent anti-inflammatory drugs, but chronic use is hampered by metabolic side effects. Therefore, there is an urgent medical need for improved GCs that are as effective as classical GCs but have a better safety profile. A well-established model to ass...

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Detalles Bibliográficos
Autores principales: Toonen, Erik J. M., Laskewitz, Anke J., van Dijk, Theo H., Bleeker, Aycha, Grefhorst, Aldo, Schouten, Annelies E., Bastiaanssen, Ellen A. J., Ballak, Dov B., Koenders, Marije I., van Doorn, Cindy, van der Vleuten, Monique A. J., van Lierop, Marie-Jose C., Groen, Albert K., Dokter, Wim H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151983/
https://www.ncbi.nlm.nih.gov/pubmed/25181348
http://dx.doi.org/10.1371/journal.pone.0098684