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Molecular Architecture of the 40S⋅eIF1⋅eIF3 Translation Initiation Complex

Eukaryotic translation initiation requires the recruitment of the large, multiprotein eIF3 complex to the 40S ribosomal subunit. We present X-ray structures of all major components of the minimal, six-subunit Saccharomyces cerevisiae eIF3 core. These structures, together with electron microscopy rec...

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Detalles Bibliográficos
Autores principales: Erzberger, Jan P., Stengel, Florian, Pellarin, Riccardo, Zhang, Suyang, Schaefer, Tanja, Aylett, Christopher H.S., Cimermančič, Peter, Boehringer, Daniel, Sali, Andrej, Aebersold, Ruedi, Ban, Nenad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151992/
https://www.ncbi.nlm.nih.gov/pubmed/25171412
http://dx.doi.org/10.1016/j.cell.2014.07.044