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Discovery of a novel (R)-selective bacterial hydroxynitrile lyase from Acidobacterium capsulatum

Hydroxynitrile lyases (HNLs) are powerful carbon–carbon bond forming enzymes. The reverse of their natural reaction – the stereoselective addition of hydrogen cyanide (HCN) to carbonyls – yields chiral cyanohydrins, versatile building blocks for the pharmaceutical and chemical industry. Recently, ba...

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Detalles Bibliográficos
Autores principales: Wiedner, Romana, Gruber-Khadjawi, Mandana, Schwab, Helmut, Steiner, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151996/
https://www.ncbi.nlm.nih.gov/pubmed/25210600
http://dx.doi.org/10.1016/j.csbj.2014.07.002