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Discovery of a novel (R)-selective bacterial hydroxynitrile lyase from Acidobacterium capsulatum
Hydroxynitrile lyases (HNLs) are powerful carbon–carbon bond forming enzymes. The reverse of their natural reaction – the stereoselective addition of hydrogen cyanide (HCN) to carbonyls – yields chiral cyanohydrins, versatile building blocks for the pharmaceutical and chemical industry. Recently, ba...
Autores principales: | Wiedner, Romana, Gruber-Khadjawi, Mandana, Schwab, Helmut, Steiner, Kerstin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151996/ https://www.ncbi.nlm.nih.gov/pubmed/25210600 http://dx.doi.org/10.1016/j.csbj.2014.07.002 |
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