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Tetramethoxychalcone, a Chalcone Derivative, Suppresses Proliferation, Blocks Cell Cycle Progression, and Induces Apoptosis of Human Ovarian Cancer Cells

In the present study, we investigated the in vitro antitumor functions of a synthetic chalcone derivative 4,3′,4′,5′- tetramethoxychalcone (TMOC) in ovarian cancer cells. We found that TMOC inhibited the proliferation and colony formation of cisplatin sensitive cell line A2780 and resistant cell lin...

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Detalles Bibliográficos
Autores principales: Qi, Zihao, Liu, Mingming, Liu, Yang, Zhang, Meiqin, Yang, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152132/
https://www.ncbi.nlm.nih.gov/pubmed/25180593
http://dx.doi.org/10.1371/journal.pone.0106206