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Plasma PCSK9 Levels Are Elevated with Acute Myocardial Infarction in Two Independent Retrospective Angiographic Studies

OBJECTIVE: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a circulating protein that promotes degradation of the low density lipoprotein (LDL) receptor. Mutations that block PCSK9 secretion reduce LDL-cholesterol and the incidence of myocardial infarction (MI). However, it remains unclear...

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Detalles Bibliográficos
Autores principales: Almontashiri, Naif A. M., Vilmundarson, Ragnar O., Ghasemzadeh, Nima, Dandona, Sonny, Roberts, Robert, Quyyumi, Arshed A., Chen, Hsiao-Huei, Stewart, Alexandre F. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152257/
https://www.ncbi.nlm.nih.gov/pubmed/25180781
http://dx.doi.org/10.1371/journal.pone.0106294