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mGluR1-Mediated Excitation of Cerebellar GABAergic Interneurons Requires Both G Protein-Dependent and Src–ERK1/2-Dependent Signaling Pathways

Stimulation of type I metabotropic glutamate receptors (mGluR1/5) in several neuronal types induces slow excitatory responses through activation of transient receptor potential canonical (TRPC) channels. GABAergic cerebellar molecular layer interneurons (MLIs) modulate firing patterns of Purkinje ce...

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Detalles Bibliográficos
Autores principales: Kubota, Hideo, Nagao, Soichi, Obata, Kunihiko, Hirono, Moritoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152260/
https://www.ncbi.nlm.nih.gov/pubmed/25181481
http://dx.doi.org/10.1371/journal.pone.0106316