Cargando…

A new tool in C. elegans reveals changes in secretory protein metabolism in ire-1-deficient animals

We recently showed that the ire-1/xbp-1 arm of the UPR plays a crucial role in maintaining basic endoplasmic reticulum (ER) functions required for the metabolism of secreted proteins even during unstressed growth conditions. During these studies we realized that although C. elegans is a powerful sys...

Descripción completa

Detalles Bibliográficos
Autores principales: Safra, Modi, Henis-Korenblit, Sivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152325/
https://www.ncbi.nlm.nih.gov/pubmed/25191629
http://dx.doi.org/10.4161/worm.27733