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A new tool in C. elegans reveals changes in secretory protein metabolism in ire-1-deficient animals
We recently showed that the ire-1/xbp-1 arm of the UPR plays a crucial role in maintaining basic endoplasmic reticulum (ER) functions required for the metabolism of secreted proteins even during unstressed growth conditions. During these studies we realized that although C. elegans is a powerful sys...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152325/ https://www.ncbi.nlm.nih.gov/pubmed/25191629 http://dx.doi.org/10.4161/worm.27733 |