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Adenosine-Mono-Phosphate-Activated Protein Kinase-Independent Effects of Metformin in T Cells
The anti-diabetic drug metformin regulates T-cell responses to immune activation and is proposed to function by regulating the energy-stress-sensing adenosine-monophosphate-activated protein kinase (AMPK). However, the molecular details of how metformin controls T cell immune responses have not been...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152329/ https://www.ncbi.nlm.nih.gov/pubmed/25181053 http://dx.doi.org/10.1371/journal.pone.0106710 |