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Adenosine-Mono-Phosphate-Activated Protein Kinase-Independent Effects of Metformin in T Cells

The anti-diabetic drug metformin regulates T-cell responses to immune activation and is proposed to function by regulating the energy-stress-sensing adenosine-monophosphate-activated protein kinase (AMPK). However, the molecular details of how metformin controls T cell immune responses have not been...

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Detalles Bibliográficos
Autores principales:	Zarrouk, Marouan, Finlay, David K., Foretz, Marc, Viollet, Benoit, Cantrell, Doreen A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152329/ https://www.ncbi.nlm.nih.gov/pubmed/25181053 http://dx.doi.org/10.1371/journal.pone.0106710

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