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Sequestration within nuclear chromocenters is not a requirement for silencing olfactory receptor transcription in a placode-derived cell line

Mouse olfaction depends on specialized olfactory sensory neurons (OSNs) that each express only one olfactory receptor protein from among a family of >1000 olfactory receptor (OR) genes encoded in the genome. To investigate epigenetic mechanisms underlying monogenic OR expression, we characterized...

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Detalles Bibliográficos
Autores principales: Kilinc, Seda, Meredith, Diane T, Lane, Robert P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152346/
https://www.ncbi.nlm.nih.gov/pubmed/25482121
http://dx.doi.org/10.4161/nucl.29343