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A novel role for interferon regulatory factor 1 (IRF1) in regulation of bone metabolism

Increased risk of bone fractures is observed in patients with chronic inflammatory conditions, such as inflammatory bowel disease and rheumatoid arthritis. Members of the Interferon Response Factor family of transcriptional regulators, IRF1 and IRF8, have been identified as genetic risk factors for...

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Detalles Bibliográficos
Autores principales: Salem, Sandra, Gao, Chan, Li, Ailian, Wang, Huifen, Nguyen-Yamamoto, Loan, Goltzman, David, Henderson, Janet E, Gros, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152406/
https://www.ncbi.nlm.nih.gov/pubmed/24954358
http://dx.doi.org/10.1111/jcmm.12327