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The impact of S6K1 kinase on neuroblastoma cell proliferation is independent of GLI1 signaling

BACKGROUND: The crosstalk between Hedgehog (HH) signaling and other signal transduction cascades has been extensively studied in different cancers. In neuroblastoma, mTOR/S6K1 signaling is known to have a role in the development of this disease and recent evidence also implicates the HH pathway. Mor...

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Detalles Bibliográficos
Autores principales: Diao, Yumei, Rahman, Mohammed Ferdous-Ur, Villegas, Victoria E, Wickström, Malin, Johnsen, John I, Zaphiropoulos, Peter G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152578/
https://www.ncbi.nlm.nih.gov/pubmed/25134527
http://dx.doi.org/10.1186/1471-2407-14-600