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Persistent hepatitis C virus infections and hepatopathological manifestations in immune-competent humanized mice

The majority of hepatitis C virus (HCV) infection develops chronic infection, which causes steatosis, cirrhosis and hepatocellular carcinoma. However, understanding HCV chronicity and pathogenesis is hampered by its narrow host range, mostly restricted to human and chimpanzee. Recent endeavour to in...

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Detalles Bibliográficos
Autores principales: Chen, Jizheng, Zhao, Yang, Zhang, Chao, Chen, Hairong, Feng, Jin, Chi, Xiumei, Pan, Yu, Du, Jun, Guo, Min, Cao, Huang, Chen, Honghe, Wang, Zilong, Pei, Rongjuan, Wang, Qian, Pan, Lei, Niu, Junqi, Chen, Xinwen, Tang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152738/
https://www.ncbi.nlm.nih.gov/pubmed/25155355
http://dx.doi.org/10.1038/cr.2014.116