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Wnt Signaling Controls the Specification of Definitive and Primitive Hematopoiesis From Human Pluripotent Stem Cells

Efforts to derive hematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) are complicated by the fact that embryonic hematopoiesis consists of two programs, primitive and definitive, that differ in developmental potential. As only definitive hematopoiesis generates HSCs, understand...

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Detalles Bibliográficos
Autores principales: Sturgeon, Christopher M., Ditadi, Andrea, Awong, Geneve, Kennedy, Marion, Keller, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152856/
https://www.ncbi.nlm.nih.gov/pubmed/24837661
http://dx.doi.org/10.1038/nbt.2915