An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts

A central goal of regenerative medicine is to generate transplantable organs from cells derived or expanded in vitro. Although numerous studies have demonstrated production of defined cell-types in vitro(1), creation of a fully intact organ has not been reported. The transcription factor Forkhead bo...

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Detalles Bibliográficos
Autores principales: Bredenkamp, Nicholas, Ulyanchenko, Svetlana, O’Neill, Kathy Emma, Manley, Nancy Ruth, Vaidya, Harsh Jayesh, Blackburn, Catherine Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153409/
https://www.ncbi.nlm.nih.gov/pubmed/25150981
http://dx.doi.org/10.1038/ncb3023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153409/
https://www.ncbi.nlm.nih.gov/pubmed/25150981
http://dx.doi.org/10.1038/ncb3023

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