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An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts
A central goal of regenerative medicine is to generate transplantable organs from cells derived or expanded in vitro. Although numerous studies have demonstrated production of defined cell-types in vitro(1), creation of a fully intact organ has not been reported. The transcription factor Forkhead bo...
Autores principales: | Bredenkamp, Nicholas, Ulyanchenko, Svetlana, O’Neill, Kathy Emma, Manley, Nancy Ruth, Vaidya, Harsh Jayesh, Blackburn, Catherine Clare |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153409/ https://www.ncbi.nlm.nih.gov/pubmed/25150981 http://dx.doi.org/10.1038/ncb3023 |
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