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rAAV/ABAD-DP-6His attenuates oxidative stress-induced injury of PC12 cells

Our previous studies have revealed that amyloid β (Aβ)-binding alcohol dehydrogenase (ABAD) decoy peptide antagonizes Aβ(42)-induced neurotoxicity. However, whether it improves oxidative stress injury remains unclear. In this study, a recombinant adenovirus constitutively secreting and expressing Aβ...

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Detalles Bibliográficos
Autores principales: Jia, Mingyue, Wang, Mingyu, Yang, Yi, Chen, Yixin, Liu, Dujuan, Wang, Xu, Song, Lei, Wu, Jiang, Yang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153500/
https://www.ncbi.nlm.nih.gov/pubmed/25206842
http://dx.doi.org/10.4103/1673-5374.130065