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Recombinant adenovirus-mediated overexpression of 3β-hydroxysteroid-Δ24 reductase

3β-Hydroxysteroid-Δ24 reductase (DHCR24) is a multifunctional enzyme that localizes to the endoplasmic reticulum and has neuroprotective and cholesterol-synthesizing activities. DHCR24 overexpression confers neuroprotection against apoptosis caused by amyloid β deposition. The present study aimed to...

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Detalles Bibliográficos
Autores principales: Lu, Xiuli, Jia, Dan, Zhao, Chenguang, Wang, Weiqi, Liu, Ting, Chen, Shuchao, Quan, Xiaoping, Sun, Deliang, Gao, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153515/
https://www.ncbi.nlm.nih.gov/pubmed/25206847
http://dx.doi.org/10.4103/1673-5374.130074