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Differential Transcriptional Effects of EGFR Inhibitors

EGF and its receptor EGFR serve as a paradigm for signaling in cell, molecular and tumor biology. EGFR inhibitors, drugs targeting the intracellular kinase activity and antibodies targeting the extracellular ligand binding, are used to treat breast, lung, colon and other cancers. Nominally affecting...

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Detalles Bibliográficos
Autor principal: Blumenberg, Miroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153546/
https://www.ncbi.nlm.nih.gov/pubmed/25184905
http://dx.doi.org/10.1371/journal.pone.0102466